Effects of diet and physical activity on adiposity and body fat distribution: implications for the prevention of cardiovascular disease.

I N T R O D U C T I O N . . 137 P R E V A L E N C E O F O B E S I T Y . . . 138 H E A L T H H A Z A R D S OF OBESITY . . 138 BODY F A T D I S T R I B U T I O N , I N S U L I N R ESI S T A NCE, H Y P E R I N S U L I N A E M I A A N D D I A B E T E S . . 139 R E G I O N A L A D I P O S E T I S S U E D I S T R I B U T I O N A N D P L A S M A L I P O P R O T E I N L E V E L S . . 140 A D I P O S E T I S S U E D I S T R I B U T I O N A N D H Y P E R T E N S I O N . . . 142 V I S C E R A L A D I P O S E T I S S U E v . M E T A B O L I C C O M P L I C A T I O N S : A C A U S A L R E L A T I O N S H I P ? . . . 143 C O N T R I B U T I O N S O F L A C K O F P H Y S I C A L A C T I V I T Y A N D A H I G H F A T D I E T T O T H E A E T I O L O G Y O F O B E S I T Y A N D R E L A T E D C O M P L I C A T I O N S . . 145 T R E A T M E N T O F OBESITY A N D R E L A T E D C O M P L I C A T I O N S . . . 146